|
gptkbp:instanceOf
|
gptkb:antiviral_drug
gptkb:prodrug
|
|
gptkbp:approvalYear
|
2002
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J05AF08
|
|
gptkbp:brand
|
gptkb:Hepsera
|
|
gptkbp:CASNumber
|
142340-99-6
|
|
gptkbp:contraindication
|
severe renal impairment
hypersensitivity to adefovir
|
|
gptkbp:developedBy
|
gptkb:Gilead_Sciences
|
|
gptkbp:drugClass
|
gptkb:nucleotide_analogue
antiviral
|
|
gptkbp:eliminationHalfLife
|
5-7 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C20H32N5O8P
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
nucleotide analogue reverse transcriptase inhibitor
|
|
gptkbp:metabolism
|
gptkb:adefovir
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:proteinBinding
|
less than 5%
|
|
gptkbp:PubChem_CID
|
60121
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
abdominal pain
headache
nephrotoxicity
lactic acidosis
asthenia
|
|
gptkbp:synonym
|
gptkb:bis(POM)_PMEA
adefovir pivoxil
|
|
gptkbp:UNII
|
31GQ7TBM5S
|
|
gptkbp:usedFor
|
chronic hepatitis B
|
|
gptkbp:bfsParent
|
gptkb:adefovir
|
|
gptkbp:bfsLayer
|
8
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
adefovir dipivoxil
|