acute tubular necrosis

GPTKB entity

Statements (35)
Predicate Object
gptkbp:instanceOf kidney disease
medical condition
gptkbp:affects kidney tubules
gptkbp:alsoKnownAs gptkb:ATN
gptkbp:cause acute kidney injury
gptkbp:characterizedBy death of tubular epithelial cells
gptkbp:commonIn ischemia
nephrotoxins
gptkbp:complication shock
hemolysis
rhabdomyolysis
gptkbp:diagnosedBy urinalysis
renal biopsy
serum creatinine
gptkbp:differentialDiagnosis acute interstitial nephritis
prerenal azotemia
gptkbp:firstDescribed 19th century
https://www.w3.org/2000/01/rdf-schema#label acute tubular necrosis
gptkbp:period maintenance phase
recovery phase
initiation phase
gptkbp:prognosis usually reversible
gptkbp:riskFactor sepsis
hypotension
major surgery
nephrotoxic drugs
gptkbp:symptom fluid overload
decreased urine output
gptkbp:treatment supportive care
dialysis
gptkbp:urineFinding muddy brown casts
gptkbp:bfsParent gptkb:renal_pathology
gptkb:intrinsic_AKI
gptkb:prerenal_AKI
gptkbp:bfsLayer 7