|
gptkbp:instance_of
|
gptkb:Ophthalmology
|
|
gptkbp:available_on
|
generic version
|
|
gptkbp:brand
|
gptkb:Zymar
|
|
gptkbp:class
|
gptkb:pharmaceuticals
fluoroquinolone antibiotic
|
|
gptkbp:clinical_trial
|
Phase III
studied in randomized controlled trials
|
|
gptkbp:clinical_use
|
ophthalmology
|
|
gptkbp:community_service
|
safety and efficacy not established in children under 1 year
|
|
gptkbp:contraindication
|
hypersensitivity to gatifloxacin
|
|
gptkbp:dosage_form
|
gptkb:Software_Solutions
|
|
gptkbp:drug_interactions
|
none known
|
|
gptkbp:duration
|
7 days
|
|
gptkbp:effective_date
|
gptkb:2003
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:formulation
|
gptkb:cream
sterile solution
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Zymar
|
|
gptkbp:indication
|
treatment of bacterial infections of the eye
|
|
gptkbp:ingredients
|
gptkb:gatifloxacin
|
|
gptkbp:invention
|
patent expired
|
|
gptkbp:lifespan
|
5 to 7 hours
|
|
gptkbp:manufacturer
|
gptkb:Allergan
|
|
gptkbp:marketed_as
|
gptkb:Canada
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:mechanism_of_action
|
inhibits bacterial DNA gyrase
|
|
gptkbp:metabolism
|
minimal hepatic metabolism
|
|
gptkbp:packaging
|
gptkb:bottle
|
|
gptkbp:patient_population
|
available online
adults and children
|
|
gptkbp:pharmacokinetics
|
well-studied
rapidly absorbed
|
|
gptkbp:price
|
varies by pharmacy
|
|
gptkbp:provides_guidance_on
|
gptkb:American_Academy_of_Ophthalmology
|
|
gptkbp:regulatory_compliance
|
FDA approved
|
|
gptkbp:requires
|
available online
prescription only
|
|
gptkbp:route_of_administration
|
topical
ocular
|
|
gptkbp:safety_features
|
generally well tolerated
|
|
gptkbp:safety_measures
|
use in lactation only if needed
use in pregnancy only if needed
|
|
gptkbp:service_frequency
|
every 2 hours for the first 2 days
|
|
gptkbp:shelf_life
|
24 months
|
|
gptkbp:side_effect
|
headache
nausea
dry eyes
vomiting
eye irritation
taste disturbance
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:used_for
|
bacterial conjunctivitis
|
|
gptkbp:bfsParent
|
gptkb:Bausch_+_Lomb_Eye_Products_Inc.
gptkb:Valeant_Pharmaceuticals
|
|
gptkbp:bfsLayer
|
6
|