Statements (13)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:monoclonal_antibody
|
| gptkbp:amendedBy |
Fc region of IgG
|
| gptkbp:effect |
increases IgG half-life
|
| gptkbp:firstDescribed |
2004
|
| gptkbp:fullName |
M252Y/S254T/T256E Fc mutation
|
| https://www.w3.org/2000/01/rdf-schema#label |
YTE
|
| gptkbp:mechanismOfAction |
increases binding to neonatal Fc receptor (FcRn)
|
| gptkbp:usedIn |
gptkb:MEDI8897
gptkb:nirsevimab antibody engineering therapeutic antibodies |
| gptkbp:bfsParent |
gptkb:Cape_Dorset_Airport
|
| gptkbp:bfsLayer |
6
|