X-linked myotubular myopathy

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:genetic_disorder
gptkb:muscular_dystrophy
gptkbp:affects gptkb:skeletal_muscle
gptkbp:alsoKnownAs XLMTM
gptkbp:category gptkb:muscular_dystrophy
gptkbp:diagnosedBy genetic testing
muscle biopsy
gptkbp:firstDescribed 1966
gptkbp:frequency 1 in 50,000 male births
gptkbp:inheritance X-linked recessive
gptkbp:mutationAssociatedWith MTM1 gene
gptkbp:namedAfter myotubular structures in muscle fibers
gptkbp:onset neonatal
gptkbp:prevalence rare
gptkbp:prognosis variable, often severe
gptkbp:symptom hypotonia
muscle weakness
respiratory difficulties
gptkbp:treatment supportive care
ventilatory support
gptkbp:bfsParent gptkb:MTM1
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label X-linked myotubular myopathy