Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
laboratory synthesis of ethers
|
| gptkbp:byproduct |
halide salt
|
| gptkbp:example |
synthesis of anisole
synthesis of diethyl ether |
| gptkbp:field |
organic chemistry
|
| gptkbp:firstDescribed |
1850
|
| https://www.w3.org/2000/01/rdf-schema#label |
Williamson ether synthesis
|
| gptkbp:limitation |
steric hindrance reduces yield
|
| gptkbp:mechanismOfAction |
S_N2
|
| gptkbp:namedAfter |
gptkb:Alexander_William_Williamson
|
| gptkbp:product |
Ether
|
| gptkbp:reactant |
alkyl halide
alkoxide |
| gptkbp:reactionCondition |
often heated
requires strong base |
| gptkbp:sideReaction |
elimination (E2) possible with secondary/tertiary halides
|
| gptkbp:solvent |
polar aprotic solvent
|
| gptkbp:type |
substitution reaction
|
| gptkbp:usedFor |
preparation of symmetrical ethers
preparation of unsymmetrical ethers |
| gptkbp:bfsParent |
gptkb:Williamson
gptkb:Ether |
| gptkbp:bfsLayer |
5
|