Statements (22)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:drug
                                        
                                         | 
                            
| gptkbp:approvalYear | 
                                    
                                        
                                            
                                            2019
                                        
                                        
                                         | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:European_Union
                                        
                                         | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            A16AX15
                                        
                                        
                                         | 
                            
| gptkbp:compatibleWith | 
                                    
                                        
                                            gptkb:United_States
                                        
                                         | 
                            
| gptkbp:developer | 
                                    
                                        
                                            gptkb:Akcea_Therapeutics
                                        
                                         gptkb:Ionis_Pharmaceuticals  | 
                            
| gptkbp:form | 
                                    
                                        
                                            
                                            solution for injection
                                        
                                        
                                         | 
                            
| gptkbp:genericName | 
                                    
                                        
                                            gptkb:volanesorsen
                                        
                                         | 
                            
| gptkbp:indication | 
                                    
                                        
                                            
                                            rare genetic lipid disorder
                                        
                                        
                                         | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            antisense oligonucleotide inhibitor of APOC3
                                        
                                        
                                         | 
                            
| gptkbp:pregnancyCategory | 
                                    
                                        
                                            
                                            not recommended
                                        
                                        
                                         | 
                            
| gptkbp:reduces | 
                                    
                                        
                                            
                                            triglyceride levels
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            subcutaneous injection
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            
                                            thrombocytopenia
                                        
                                        
                                         injection site reactions  | 
                            
| gptkbp:target | 
                                    
                                        
                                            
                                            APOC3 mRNA
                                        
                                        
                                         | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            gptkb:familial_chylomicronemia_syndrome
                                        
                                         | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Ionis_Pharmaceuticals
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            6
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            Waylivra
                                        
                                        
                                         |