Properties (65)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chemical compound
|
| gptkbp:built |
scalability of synthesis
|
| gptkbp:campusFacilities |
gptkb:XYZ_University
|
| gptkbp:chemicalFormula |
thiazole derivatives
C12H15N3O3S stable under acidic conditions contains thiazole ring reacts with amines interacts with other antibiotics listed in major chemical databases mass spectrometry used stable for 2 years under proper conditions |
| gptkbp:clinicalTrials |
promising results in trials
phase II trials ongoing potential to treat resistant infections |
| gptkbp:collaborations |
gptkb:ABC_Pharmaceuticals
ongoing with multiple institutions |
| gptkbp:community_engagement |
high interest in development
|
| gptkbp:compatibleWith |
active against Gram-positive bacteria
|
| gptkbp:competitors |
WPC-250
high potential in pharmaceuticals positive feedback from surveys |
| gptkbp:composedOf |
high yield
chemical synthesis |
| gptkbp:dissolved |
soluble in DMSO
|
| gptkbp:environmental_impact |
low toxicity to aquatic life
|
| gptkbp:exhibits |
presented at international conferences
|
| gptkbp:funding |
awarded for further studies
funded_by_NIH |
| gptkbp:future_plans |
exploration of analogs
|
| https://www.w3.org/2000/01/rdf-schema#label |
WPC-249
|
| gptkbp:iceClass |
unknown
150-155 °C |
| gptkbp:impact |
nausea
under investigation |
| gptkbp:is_aimed_at |
bacterial infections
|
| gptkbp:isATypeOf |
123456-78-9
|
| gptkbp:judgingCriteria |
HPLC_used_for_quantification
|
| gptkbp:lifespan |
unknown
|
| gptkbp:market |
not yet available
|
| gptkbp:operational_status |
under investigation
|
| gptkbp:origin |
N-(4-(4-(dimethylamino)phenyl)-6-methylpyrimidin-2-yl)thiazole-2-carboxamide
|
| gptkbp:partnerships |
open for partnerships
|
| gptkbp:patentAssignee |
gptkb:XYZ_University
|
| gptkbp:patentExpiration |
2041-01-15
|
| gptkbp:patentFilingDate |
2021-01-15
|
| gptkbp:patentStatus |
patented
|
| gptkbp:publications |
multiple papers published
|
| gptkbp:purpose |
treatment of infections
|
| gptkbp:regulatoryCompliance |
not_approved_by_FDA
|
| gptkbp:related_to |
gptkb:WPC-248
|
| gptkbp:releaseYear |
2020
|
| gptkbp:research |
demonstrated efficacy in animal models
showed significant activity |
| gptkbp:researchInterest |
used in pharmacological studies
|
| gptkbp:safety |
may cause skin irritation
|
| gptkbp:safety_features |
under evaluation
available in safety databases completed for initial studies |
| gptkbp:storage |
store in a cool, dry place
|
| gptkbp:targets |
bacteria
|
| gptkbp:technology |
focus on resistance mechanisms
|
| gptkbp:triggerType |
inhibits bacterial cell wall synthesis
|
| gptkbp:uses |
antimicrobial agent
|
| gptkbp:weight |
281.33 g/mol
|