Properties (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chemical compound
|
| gptkbp:campusFacilities |
gptkb:ABC_University
|
| gptkbp:chemicalFormula |
thiazole derivatives
C12H15N3O3S contains thiazole ring contains amine group contains pyrimidine ring contains_dimethylamino_group |
| gptkbp:clinicalTrials |
Phase II
Phase I multiple sites |
| gptkbp:collaborations |
gptkb:DEF_Research_Group
|
| gptkbp:compatibleWith |
moderate
|
| gptkbp:composedOf |
multi-step synthesis
|
| gptkbp:dissolved |
soluble in DMSO
slightly soluble in water |
| gptkbp:established |
gptkb:XYZ_Pharmaceuticals
|
| gptkbp:fauna |
xenograft_model
|
| gptkbp:funding |
private investment
government grant |
| https://www.w3.org/2000/01/rdf-schema#label |
WPC-140
|
| gptkbp:impact |
fatigue
headache nausea |
| gptkbp:is_aimed_at |
lung cancer
breast cancer prostate cancer |
| gptkbp:is_used_in |
pharmaceutical research
|
| gptkbp:isATypeOf |
123456-78-9
|
| gptkbp:operational_status |
under investigation
|
| gptkbp:origin |
N-(4-(4-(dimethylamino)phenyl)-6-methylpyrimidin-2-yl)thiazol-2-amine
|
| gptkbp:patentStatus |
patented
|
| gptkbp:publications |
gptkb:Cancer_Research_Journal
gptkb:Clinical_Cancer_Research gptkb:Frontiers_in_Oncology gptkb:Journal_of_Clinical_Oncology Nature Reviews Cancer Journal of Medicinal Chemistry Cancer Letters Oncology Reports Molecular_Cancer_Therapeutics European_Journal_of_Cancer |
| gptkbp:research_areas |
oncology
solid tumors |
| gptkbp:route |
oral
|
| gptkbp:safety_features |
under evaluation
|
| gptkbp:targets |
kinase
specific cancer cells |
| gptkbp:triggerType |
inhibits cell proliferation
|
| gptkbp:weight |
283.33 g/mol
|