Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
pharmaceutical chemistry
asymmetric synthesis total synthesis |
| gptkbp:catalyzes |
palladium
|
| gptkbp:commonLigand |
phosphine ligand
|
| gptkbp:discoveredIn |
1965
|
| gptkbp:field |
organic chemistry
|
| https://www.w3.org/2000/01/rdf-schema#label |
Tsuji–Trost reaction
|
| gptkbp:importantFor |
enables regioselective and stereoselective synthesis
|
| gptkbp:mechanismOfAction |
formation of π-allyl palladium complex
|
| gptkbp:namedAfter |
gptkb:Barry_Trost
Jiro Tsuji |
| gptkbp:nucleophile |
various nucleophiles
|
| gptkbp:product |
substituted allylic compound
|
| gptkbp:relatedTo |
transition metal catalysis
allylic alkylation |
| gptkbp:solvent |
gptkb:THF
gptkb:DMF acetonitrile |
| gptkbp:step |
nucleophilic attack on π-allyl palladium intermediate
|
| gptkbp:substrate |
allylic compound
|
| gptkbp:type |
palladium-catalyzed allylic substitution
|
| gptkbp:bfsParent |
gptkb:Trost_ligand
|
| gptkbp:bfsLayer |
7
|