TransCon PTH

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:drug
parathyroid hormone replacement therapy
gptkbp:activeIngredient parathyroid hormone (PTH 1-34)
gptkbp:approvalYear 2023
gptkbp:ATCCode H05AA10
gptkbp:brand Palopegteriparatide
Yorvipath
gptkbp:clinicalTrialPhase Phase 3
gptkbp:developedBy gptkb:Ascendis_Pharma
gptkbp:effect decreases serum phosphate
increases serum calcium
reduces need for oral calcium and vitamin D supplements
gptkbp:form injection
gptkbp:halfLife approximately 60 hours
https://www.w3.org/2000/01/rdf-schema#label TransCon PTH
gptkbp:indication gptkb:hypoparathyroidism
gptkbp:mechanismOfAction parathyroid hormone prodrug
gptkbp:regulates approved in the United States
gptkbp:routeOfAdministration subcutaneous injection
gptkbp:target parathyroid hormone receptor
gptkbp:therapeuticArea endocrinology
gptkbp:bfsParent gptkb:Ascendis_Pharma
gptkbp:bfsLayer 8