Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
parathyroid hormone replacement therapy |
gptkbp:activeIngredient |
parathyroid hormone (PTH 1-34)
|
gptkbp:approvalYear |
2023
|
gptkbp:ATCCode |
H05AA10
|
gptkbp:brand |
Palopegteriparatide
Yorvipath |
gptkbp:clinicalTrialPhase |
Phase 3
|
gptkbp:developedBy |
gptkb:Ascendis_Pharma
|
gptkbp:effect |
decreases serum phosphate
increases serum calcium reduces need for oral calcium and vitamin D supplements |
gptkbp:form |
injection
|
gptkbp:halfLife |
approximately 60 hours
|
https://www.w3.org/2000/01/rdf-schema#label |
TransCon PTH
|
gptkbp:indication |
gptkb:hypoparathyroidism
|
gptkbp:mechanismOfAction |
parathyroid hormone prodrug
|
gptkbp:regulates |
approved in the United States
|
gptkbp:routeOfAdministration |
subcutaneous injection
|
gptkbp:target |
parathyroid hormone receptor
|
gptkbp:therapeuticArea |
endocrinology
|
gptkbp:bfsParent |
gptkb:Ascendis_Pharma
|
gptkbp:bfsLayer |
8
|