Statements (71)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antibiotic
|
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:availableIn |
generic drug
|
| gptkbp:brand |
Nebcin
TOBI |
| gptkbp:built |
Streptomyces tenebrarius
|
| gptkbp:chemicalFormula |
C18H37N5O9
|
| gptkbp:contraindication |
renal impairment
allergy to aminoglycosides |
| gptkbp:drugInterdiction |
renal excretion
|
| gptkbp:endOfLife |
2-3 hours
|
| gptkbp:formulation |
ophthalmic solution
inhalation powder |
| gptkbp:hasActivities |
broad-spectrum
|
| https://www.w3.org/2000/01/rdf-schema#label |
Tobramycin
|
| gptkbp:impact |
meningitis
pneumonia sepsis cystic fibrosis skin infections otitis media bacterial conjunctivitis urinary tract infections endocarditis bacterial pneumonia bacterial meningitis bacterial throat infections bacterial arthritis bacterial bloodstream infections bacterial central nervous system infections bacterial dental infections bacterial ear infections bacterial endophthalmitis bacterial eye infections bacterial gastrointestinal infections bacterial genital infections bacterial heart infections bacterial intra-abdominal infections bacterial joint infections bacterial keratitis bacterial lung infections bacterial oral infections bacterial osteomyelitis bacterial pelvic infections bacterial perianal infections bacterial rectal infections bacterial respiratory and systemic infections bacterial respiratory infections bacterial respiratory tract infections bacterial sepsis bacterial sinus infections bacterial skin and soft tissue infections bacterial skin infections bacterial soft tissue infections bacterial systemic infections bacterial urinary tract infections bacterial vaginal infections bacterial wound infections bone infections |
| gptkbp:interactsWith |
muscle relaxants
other nephrotoxic drugs |
| gptkbp:issuedBy |
injection
inhalation solution |
| gptkbp:locatedIn |
1967
|
| gptkbp:route |
intravenous
topical |
| gptkbp:sideEffect |
nephrotoxicity
ototoxicity |
| gptkbp:targets |
Pseudomonas aeruginosa
|
| gptkbp:triggerType |
inhibits protein synthesis
|
| gptkbp:usedFor |
bacterial infections
|