The evolutionary history of 2,658 cancers
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:academic_journal
|
| gptkbp:author |
Iñigo Martincorena
Moritz Gerstung PCAWG Evolution & Heterogeneity Working Group Peter J. Campbell Peter J. Park Yilong Li |
| gptkbp:doi |
10.1038/s41586-019-1907-7
|
| gptkbp:foundIn |
Most driver mutations occur early in tumor evolution
Copy number changes are often late events Different cancer types have distinct evolutionary trajectories |
| https://www.w3.org/2000/01/rdf-schema#label |
The evolutionary history of 2,658 cancers
|
| gptkbp:notableProject |
gptkb:Pan-Cancer_Analysis_of_Whole_Genomes_(PCAWG)
|
| gptkbp:openAccess |
yes
|
| gptkbp:pages |
122-128
|
| gptkbp:publicationDate |
2020-02-05
|
| gptkbp:publishedIn |
gptkb:Nature
|
| gptkbp:size |
2,658 cancer genomes
|
| gptkbp:topic |
genomic analysis
cancer evolution mutation timing tumor heterogeneity |
| gptkbp:volume |
578
|
| gptkbp:bfsParent |
gptkb:Nature_2020_Pan-Cancer_Analysis_papers
|
| gptkbp:bfsLayer |
7
|