|
gptkbp:instanceOf
|
alcohol addiction treatment
|
|
gptkbp:advocatesFor
|
gptkb:Claudia_Christian
|
|
gptkbp:alternativeTo
|
abstinence-based treatments
|
|
gptkbp:basedOn
|
pharmacological extinction
|
|
gptkbp:controversy
|
not widely adopted in all countries
|
|
gptkbp:developedBy
|
gptkb:Dr._John_David_Sinclair
|
|
gptkbp:evidenceBase
|
clinical trials in Finland
|
|
gptkbp:featuredIn
|
gptkb:One_Little_Pill_(documentary)
|
|
gptkbp:firstDescribed
|
1990s
|
|
gptkbp:goal
|
achieve abstinence
enable controlled drinking
reduce alcohol cravings
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
The Sinclair Method
|
|
gptkbp:mechanismOfAction
|
opioid receptor blockade
|
|
gptkbp:notRecommendedFor
|
people using opioids
people with liver failure
|
|
gptkbp:popularizedBy
|
gptkb:Finland
|
|
gptkbp:principle
|
take medication before drinking
|
|
gptkbp:requires
|
medical supervision
patient compliance
|
|
gptkbp:sideEffect
|
nausea
fatigue
headache
|
|
gptkbp:successRate
|
up to 78% in some studies
|
|
gptkbp:treatment
|
alcohol use disorder
|
|
gptkbp:usedIn
|
gptkb:Australia
gptkb:Europe
gptkb:United_States
|
|
gptkbp:usesMedication
|
gptkb:naltrexone
nalmefene
|
|
gptkbp:bfsParent
|
gptkb:Claudia_Christian
|
|
gptkbp:bfsLayer
|
6
|