Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Analytical Technique
|
| gptkbp:advantage |
Quantitative Analysis
High Sensitivity High Specificity Structural Information |
| gptkbp:alsoKnownAs |
MS/MS
|
| gptkbp:commonInstrumentType |
gptkb:Orbitrap
gptkb:Triple_Quadrupole gptkb:Time-of-Flight_(TOF) Fourier Transform Ion Cyclotron Resonance (FT-ICR) Ion Trap |
| gptkbp:component |
Ion Source
Collision Cell Multiple Mass Analyzers |
| gptkbp:enables |
gptkb:Newborn_Screening
Environmental Analysis Detection of Small Molecules Drug Metabolite Identification Food Safety Testing Identification of Biomolecules Peptide Sequencing Post-Translational Modification Analysis Toxicology Testing |
| gptkbp:firstDescribed |
1970s
|
| gptkbp:fragmentationMethod |
Collision-Induced Dissociation (CID)
Electron Transfer Dissociation (ETD) Higher-energy Collisional Dissociation (HCD) Surface-Induced Dissociation (SID) |
| https://www.w3.org/2000/01/rdf-schema#label |
Tandem Mass Spectrometry
|
| gptkbp:inventedBy |
Alfred Yergey
|
| gptkbp:limitation |
Complex Data Interpretation
Instrument Cost Sample Preparation Requirements |
| gptkbp:output |
Multiple Reaction Monitoring (MRM)
Neutral Loss Spectrum Precursor Ion Spectrum Product Ion Spectrum Selected Reaction Monitoring (SRM) |
| gptkbp:principle |
Fragmentation of Ions
Sequential Mass Analysis |
| gptkbp:relatedTo |
gptkb:Gas_Chromatography
gptkb:Liquid_Chromatography Mass Spectrometry |
| gptkbp:requires |
detector
Ionization Vacuum System |
| gptkbp:usedFor |
Quantification of Compounds
Structural Elucidation |
| gptkbp:usedIn |
gptkb:Metabolomics
Pharmacokinetics Proteomics Clinical Diagnostics |
| gptkbp:bfsParent |
gptkb:spectrometer
|
| gptkbp:bfsLayer |
5
|