T cell receptor fusion construct (TRuC) platform
GPTKB entity
Statements (16)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
immunotherapy platform
|
| gptkbp:clinicalTrialPhase |
solid tumors
hematologic malignancies |
| gptkbp:developedBy |
gptkb:TCR2_Therapeutics
|
| gptkbp:distinctFrom |
gene therapy
TCR-T cell therapy |
| gptkbp:feature |
MHC-independent antigen recognition
engages full TCR signaling machinery fusion of antibody-based binding domain to TCR complex |
| https://www.w3.org/2000/01/rdf-schema#label |
T cell receptor fusion construct (TRuC) platform
|
| gptkbp:mechanismOfAction |
redirects T cells to target tumor cells
|
| gptkbp:target |
tumor antigens
|
| gptkbp:technology |
gene therapy
|
| gptkbp:usedFor |
immunotherapy
|
| gptkbp:bfsParent |
gptkb:TCR2_Therapeutics
|
| gptkbp:bfsLayer |
8
|