Statements (14)
Predicate | Object |
---|---|
gptkbp:instanceOf |
genetic disorder
|
gptkbp:aminoAcidChange |
threonine to methionine at position 790
|
gptkbp:associatedWith |
gptkb:non-small_cell_lung_cancer
|
gptkbp:category |
somatic mutation
|
gptkbp:detects |
molecular testing
|
gptkbp:firstDescribed |
2005
|
gptkbp:foundIn |
gptkb:EGFR_gene
|
https://www.w3.org/2000/01/rdf-schema#label |
T790M mutation
|
gptkbp:relatedTo |
acquired resistance
|
gptkbp:resistantTo |
gptkb:EGFR_tyrosine_kinase_inhibitors
|
gptkbp:target |
gptkb:osimertinib
|
gptkbp:bfsParent |
gptkb:EGFR_mutation-positive_NSCLC
gptkb:EGFR_tyrosine_kinase_inhibitors |
gptkbp:bfsLayer |
7
|