Statements (37)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antibacterial drug
sulfonamide antibiotic |
| gptkbp:affiliatedWith |
WHO Essential Medicines List (veterinary)
|
| gptkbp:ATCCode |
gptkb:J01EB03
|
| gptkbp:CASNumber |
57-68-1
|
| gptkbp:category |
gptkb:veterinary_medicine
antimicrobial |
| gptkbp:chemicalFormula |
C12H14N4O2S
|
| gptkbp:contraindication |
hypersensitivity to sulfonamides
|
| gptkbp:discoveredBy |
1940s
|
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
Sulfamethazine
|
| gptkbp:IUPACName |
4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide
|
| gptkbp:KEGGID |
D00462
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits dihydropteroate synthase
|
| gptkbp:meltingPoint |
196–200 °C
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
278.33 g/mol
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL1431
5137 5326 |
| gptkbp:regulates |
residues monitored in food animals
|
| gptkbp:riskFactor |
potential for antimicrobial resistance
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
allergic reactions
crystalluria hematologic disorders |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:synonym |
sulfadimidine
|
| gptkbp:UNII |
Q1J8A4J354
|
| gptkbp:used_in |
gptkb:veterinary_medicine
food-producing animals |
| gptkbp:usedFor |
treatment of bacterial infections
|
| gptkbp:bfsParent |
gptkb:SMT
|
| gptkbp:bfsLayer |
7
|