|
gptkbp:instanceOf
|
gptkb:antibacterial_drug
gptkb:sulfonamide_antibiotic
|
|
gptkbp:affiliatedWith
|
WHO Essential Medicines List (veterinary)
|
|
gptkbp:ATCCode
|
gptkb:J01EB03
|
|
gptkbp:CASNumber
|
57-68-1
|
|
gptkbp:category
|
gptkb:veterinary_medicine
antimicrobial
|
|
gptkbp:chemicalFormula
|
C12H14N4O2S
|
|
gptkbp:contraindication
|
hypersensitivity to sulfonamides
|
|
gptkbp:discoveredBy
|
1940s
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:IUPACName
|
4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide
|
|
gptkbp:KEGGID
|
D00462
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits dihydropteroate synthase
|
|
gptkbp:meltingPoint
|
196–200 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
278.33 g/mol
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1431
5137
5326
|
|
gptkbp:regulates
|
residues monitored in food animals
|
|
gptkbp:riskFactor
|
potential for antimicrobial resistance
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
allergic reactions
crystalluria
hematologic disorders
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:synonym
|
sulfadimidine
|
|
gptkbp:UNII
|
Q1J8A4J354
|
|
gptkbp:used_in
|
gptkb:veterinary_medicine
food-producing animals
|
|
gptkbp:usedFor
|
treatment of bacterial infections
|
|
gptkbp:bfsParent
|
gptkb:SMT
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sulfamethazine
|