Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
bioorthogonal chemistry
glycobiology protein labeling |
| gptkbp:developedBy |
gptkb:Carolyn_R._Bertozzi
gptkb:Benjamin_G._Davis |
| gptkbp:feature |
bioorthogonal
mild reaction conditions does not require metal catalyst selective for azides |
| gptkbp:field |
chemical biology
organic chemistry bioconjugation |
| https://www.w3.org/2000/01/rdf-schema#label |
Staudinger ligation
|
| gptkbp:introducedIn |
2000
|
| gptkbp:mechanismOfAction |
formation of iminophosphorane intermediate
hydrolysis to amide |
| gptkbp:namedAfter |
gptkb:Hermann_Staudinger
|
| gptkbp:produces |
amide bond
|
| gptkbp:relatedTo |
gptkb:Staudinger_reaction
|
| gptkbp:uses |
azide
phosphine |
| gptkbp:bfsParent |
gptkb:Staudinger_reaction
|
| gptkbp:bfsLayer |
7
|