Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:anatomical_structure
|
| gptkbp:alsoKnownAs |
organizer
|
| gptkbp:category |
developmental biology
embryology |
| gptkbp:contains |
gptkb:chordin
gptkb:follistatin BMP inhibitors noggin signaling molecules |
| gptkbp:discoveredBy |
gptkb:Hans_Spemann
gptkb:Hilde_Mangold |
| gptkbp:discoveredIn |
1924
|
| gptkbp:effect |
induces secondary embryonic axis when transplanted
|
| gptkbp:experimentType |
transplantation experiment
|
| gptkbp:foundIn |
amphibian embryos
|
| gptkbp:function |
induces formation of the neural tube
organizes embryonic axis |
| gptkbp:historicalSignificance |
first demonstration of embryonic induction
|
| gptkbp:homologousStructure |
Hensen's node (in birds)
node (in mammals) shield (in fish) |
| https://www.w3.org/2000/01/rdf-schema#label |
Spemann-Mangold organizer
|
| gptkbp:inducedBy |
dorsalization
mesoderm differentiation neural tissue |
| gptkbp:influenced |
developmental biology
|
| gptkbp:location |
dorsal lip of the blastopore
|
| gptkbp:modelOrganismFor |
gptkb:Xenopus_laevis
|
| gptkbp:NobelPrizeYear |
Hans Spemann won Nobel Prize in Physiology or Medicine in 1935
|
| gptkbp:role |
gastrulation
body axis formation |
| gptkbp:species |
vertebrates
|
| gptkbp:bfsParent |
gptkb:Hans_Spemann
|
| gptkbp:bfsLayer |
5
|