Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:approvalYear |
2012
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
J04AK05
|
| gptkbp:CASNumber |
843663-66-1
|
| gptkbp:chemicalFormula |
C32H31BrN2O2
|
| gptkbp:contraindication |
severe hepatic impairment
|
| gptkbp:genericName |
gptkb:bedaquiline
|
| https://www.w3.org/2000/01/rdf-schema#label |
Sirturo
|
| gptkbp:legalStatus |
Rx-only
|
| gptkbp:manufacturer |
gptkb:Janssen_Pharmaceuticals
|
| gptkbp:mechanismOfAction |
inhibits mycobacterial ATP synthase
|
| gptkbp:pregnancyCategory |
Not recommended
|
| gptkbp:prescriptionStatus |
prescription only
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
headache QT prolongation arthralgia |
| gptkbp:usedFor |
treatment of multidrug-resistant tuberculosis
|
| gptkbp:bfsParent |
gptkb:Janssen_Pharmaceutica
gptkb:Janssen_Sciences gptkb:BDQ |
| gptkbp:bfsLayer |
7
|