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Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:clinical_trial
|
| gptkbp:advantage |
Complex Statistical Analysis
Faster Decision Making Potential for Operational Bias Resource Savings |
| gptkbp:feature |
Adaptive Design
Early Stopping Rules Interim Analysis |
| gptkbp:firstDescribed |
gptkb:Abraham_Wald
|
| gptkbp:goal |
Ethical Considerations
Increase Efficiency Reduce Sample Size |
| gptkbp:introducedIn |
1940s
|
| gptkbp:regulates |
gptkb:EMA_Guidelines
gptkb:FDA_Guidelines |
| gptkbp:relatedTo |
Bayesian Sequential Trials
Group Sequential Design Sequential Probability Ratio Test |
| gptkbp:requires |
Pre-specified Stopping Rules
Statistical Monitoring Board |
| gptkbp:usedIn |
gptkb:Drug_Development
gptkb:Medical_Research Biostatistics |
| gptkbp:bfsParent |
gptkb:Peter_Armitage
|
| gptkbp:bfsLayer |
4
|
| https://www.w3.org/2000/01/rdf-schema#label |
Sequential Medical Trials
|