Schizophrenia, Chronic

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf mental disorder
gptkbp:associatedWith stigma
suicide risk
poor physical health
gptkbp:canBeChronic if untreated
despite treatment
gptkbp:cause homelessness
substance abuse
disability
social withdrawal
reduced life expectancy
occupational dysfunction
gptkbp:characterizedBy long-term impairment
persistent psychotic symptoms
gptkbp:diagnosedBy gptkb:DSM-5_criteria
clinical assessment
gptkbp:differentialDiagnosis gptkb:schizoaffective_disorder
bipolar disorder
major depressive disorder with psychotic features
gptkbp:firstDescribed gptkb:Emil_Kraepelin
gptkbp:hasNegativeSymptoms gptkb:anhedonia
social withdrawal
alogia
avolition
blunted affect
gptkbp:hasPositiveSymptoms hallucinations
delusions
thought disorder
disorganized behavior
https://www.w3.org/2000/01/rdf-schema#label Schizophrenia, Chronic
gptkbp:ICD-10_code F20.5
gptkbp:mayInclude hallucinations
cognitive deficits
delusions
disorganized thinking
negative symptoms
gptkbp:onset late adolescence or early adulthood
gptkbp:prevalence about 1% of population
gptkbp:prognosis variable
gptkbp:requires long-term care
gptkbp:riskFactor cannabis use
family history of schizophrenia
prenatal stress
urban upbringing
gptkbp:subspecies schizophrenia
gptkbp:treatment antipsychotic medications
psychosocial interventions
gptkbp:bfsParent gptkb:D012852
gptkbp:bfsLayer 7