Statements (50)
Predicate | Object |
---|---|
gptkbp:instanceOf |
chemical compound
|
gptkbp:ADC |
favorable
|
gptkbp:behavior |
improves mood
|
gptkbp:built |
regulatory hurdles
|
gptkbp:campusFacilities |
gptkb:XYZ_University
|
gptkbp:chemicalFormula |
thiazole derivatives
lipophilic thiazole ring C20H22N2O2S stable in solution |
gptkbp:classification |
novel antidepressant
|
gptkbp:clinicalTrials |
ongoing
potentially significant |
gptkbp:collaborations |
gptkb:ABC_Pharmaceuticals
international collaboration |
gptkbp:compatibleWith |
antidepressant
|
gptkbp:composedOf |
multi-step organic synthesis
|
gptkbp:dissolved |
soluble in DMSO
|
gptkbp:environmentalImpact |
low toxicity
|
gptkbp:fauna |
rat model of depression
|
gptkbp:financial_aid |
stable under normal conditions
|
gptkbp:firstClaim |
treatment of anxiety
|
gptkbp:formulation |
oral administration
|
gptkbp:funding |
government grant
|
gptkbp:future_plans |
further studies required
|
https://www.w3.org/2000/01/rdf-schema#label |
SR 835
|
gptkbp:impact |
unknown
|
gptkbp:isATypeOf |
123456-78-9
|
gptkbp:market |
not marketed
|
gptkbp:operational_status |
investigational new drug
preclinical |
gptkbp:origin |
N-(4-(4-(dimethylamino)phenyl)-2-methylphenyl)-2-methyl-2-(4-methylphenyl)thiazole-4-carboxamide
|
gptkbp:patentAssignee |
gptkb:XYZ_University
|
gptkbp:patentStatus |
patented
|
gptkbp:publications |
gptkb:Journal_of_Neuroscience
|
gptkbp:regulatoryBody |
high affinity
|
gptkbp:related_to |
SR 57746A
|
gptkbp:releaseYear |
2000
|
gptkbp:research_areas |
psychiatry
|
gptkbp:research_focus |
discovery phase
mood disorders |
gptkbp:researchAndDevelopment |
promising results
|
gptkbp:safety_features |
not fully established
|
gptkbp:safetyFeatures |
required
|
gptkbp:storage |
cool, dry place
|
gptkbp:targets |
5-HT receptor
serotonin receptor |
gptkbp:triggerType |
serotonin reuptake inhibition
|
gptkbp:uses |
research in neuroscience
|
gptkbp:weight |
350.47 g/mol
|