Properties (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
think tank
|
| gptkbp:associated_with |
diabetes
hypertension metabolic syndrome obesity neurological disorders renal tubular acidosis cystic fibrosis heart disease gastrointestinal disorders metabolic alkalosis |
| gptkbp:associatedWith |
acid-base balance
|
| gptkbp:clinicalTrials |
kidney function
acid-base disorders bicarbonate transport disorders disorders related to bicarbonate transport |
| gptkbp:community |
brain
kidney pancreas |
| gptkbp:constructionMaterial |
bicarbonate ions
sodium ions |
| gptkbp:culturalEvents |
SLC4A4 in humans
SLC4A4 in mice SLC4A4 in rats |
| gptkbp:environmentalProtection |
influencing cellular signaling
maintaining pH balance regulating electrolyte levels supporting metabolic processes |
| gptkbp:family |
solute carrier family
|
| gptkbp:function |
sodium bicarbonate transport
|
| gptkbp:geneticDiversity |
SLC4A4
associated with metabolic disorders |
| https://www.w3.org/2000/01/rdf-schema#label |
SLC-4E
|
| gptkbp:interactsWith |
with bicarbonate
with other transporters with sodium |
| gptkbp:is_a_route_for |
cerebrospinal fluid regulation
renal bicarbonate reabsorption |
| gptkbp:location |
cell membrane
|
| gptkbp:regulates |
environmental factors
hormonal control cellular conditions |
| gptkbp:research |
gene regulation
transport mechanisms pathophysiology of diseases pharmacological targets physiological roles |
| gptkbp:research_areas |
for drug development
for enzyme replacement therapy for gene therapy for monoclonal antibodies for small molecule inhibitors |
| gptkbp:structureType |
transporter protein
|