Roberts syndrome

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:genetic_disorder
gptkb:rare_disease
gptkbp:affects both sexes
gptkbp:alsoKnownAs SC phocomelia
pseudothalidomide syndrome
gptkbp:associatedWith mitotic abnormalities
premature centromere separation
gptkbp:characterizedBy gptkb:intellectual_disability
microcephaly
cleft lip
cleft palate
craniofacial abnormalities
limb malformations
growth retardation
gptkbp:diagnosedBy clinical evaluation
genetic testing
gptkbp:firstDescribed 1919
John Bingham Roberts
gptkbp:inheritance autosomal recessive
gptkbp:mutationAssociatedWith ESCO2 gene
gptkbp:OMIM 268300
gptkbp:prevalence very rare
gptkbp:prognosis variable
gptkbp:treatment supportive care
surgical intervention
gptkbp:bfsParent gptkb:ESCO1
gptkb:ESCO2
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label Roberts syndrome