Statements (57)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:immunotherapy
|
gptkbp:approves |
gptkb:1999
gptkb:FDA |
gptkbp:atccode |
J05 AH01
|
gptkbp:availability |
pharmacies
prescription only |
gptkbp:bioavailability |
not applicable
|
gptkbp:casnumber |
139110-80-8
|
gptkbp:clinical_trial |
Phase III
ongoing studies for efficacy |
gptkbp:clinical_use |
pandemic influenza
seasonal influenza |
gptkbp:contraindication |
history of asthma
children under 5 years history of COPD |
gptkbp:developed_by |
gptkb:Glaxo_Smith_Kline
|
gptkbp:dosage_form |
inhalation powder
|
gptkbp:drug_interactions |
may interact with other antiviral drugs
|
gptkbp:excretion |
urine
|
gptkbp:formulation |
dry powder inhaler
powder for inhalation |
https://www.w3.org/2000/01/rdf-schema#label |
Relenza
|
gptkbp:indication |
prophylaxis of influenza
|
gptkbp:ingredients |
gptkb:zanamivir
|
gptkbp:invention |
patented
|
gptkbp:lifespan |
2.5 to 5 hours
|
gptkbp:marketed_as |
gptkb:Relenza
multiple countries |
gptkbp:mechanism_of_action |
neuraminidase inhibitor
|
gptkbp:metabolism |
minimal hepatic metabolism
|
gptkbp:name |
essential medicines
|
gptkbp:packaging |
blister packs
|
gptkbp:patient_education |
instruct on proper inhalation technique
|
gptkbp:patient_population |
adults and children
|
gptkbp:price |
varies by region
|
gptkbp:provides_guidance_on |
CDC recommends use during outbreaks
WHO recommends use during pandemics |
gptkbp:requires |
available online
|
gptkbp:research |
investigated for other viral infections
|
gptkbp:research_focus |
influenza resistance
|
gptkbp:route_of_administration |
inhalation
|
gptkbp:safety_features |
generally well tolerated
|
gptkbp:safety_measures |
monitor for respiratory issues
|
gptkbp:shelf_life |
3 years
|
gptkbp:side_effect |
headache
nausea allergic reactions cough bronchospasm throat irritation neuropsychiatric events |
gptkbp:storage |
store at room temperature
|
gptkbp:structure |
C12 H20 N4 O7 S
|
gptkbp:trade |
gptkb:zanamivir
|
gptkbp:used_for |
treatment of influenza
|
gptkbp:bfsParent |
gptkb:zanamivir
|
gptkbp:bfsLayer |
5
|