|
gptkbp:instanceOf
|
gptkb:progestogen
hormone
|
|
gptkbp:ATCCode
|
G03DA04
|
|
gptkbp:boilingPoint
|
447.6 °C
|
|
gptkbp:CASNumber
|
57-83-0
|
|
gptkbp:chemicalFormula
|
C21H30O2
|
|
gptkbp:color
|
white to off-white crystalline powder
|
|
gptkbp:discoveredBy
|
gptkb:George_W._Corner
gptkb:Willard_Myron_Allen
|
|
gptkbp:discoveredIn
|
1933
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
humans
mammals
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Progesterone
|
|
gptkbp:IUPACName
|
gptkb:pregn-4-ene-3,20-dione
|
|
gptkbp:KEGGID
|
C00418
|
|
gptkbp:meltingPoint
|
126 °C
|
|
gptkbp:MeSH_ID
|
D011374
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
314.47 g/mol
|
|
gptkbp:predecessor
|
gptkb:androgens
corticosteroids
estrogens
|
|
gptkbp:producedBy
|
gptkb:placenta
adrenal glands
ovaries
|
|
gptkbp:PubChem_CID
|
5994
CHEBI:17026
DB00396
CHEMBL1030
|
|
gptkbp:role
|
maintenance of pregnancy
regulation of menstrual cycle
development of mammary glands
preparation of endometrium for implantation
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
transdermal
vaginal
|
|
gptkbp:sideEffect
|
headache
breast tenderness
mood changes
drowsiness
|
|
gptkbp:solubility
|
insoluble in water
soluble in organic solvents
|
|
gptkbp:synonym
|
gptkb:P4
gptkb:pregn-4-ene-3,20-dione
|
|
gptkbp:UNII
|
4G7DS2Q64Y
|
|
gptkbp:used_in
|
hormone replacement therapy
contraceptives
treatment of abnormal uterine bleeding
treatment of amenorrhea
|
|
gptkbp:bfsParent
|
gptkb:Uterus
gptkb:Cholesterol
|
|
gptkbp:bfsLayer
|
6
|