gptkbp:instanceOf
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person
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gptkbp:affiliation
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gptkb:University_of_Oxford
gptkb:National_Institute_for_Medical_Research
gptkb:Francis_Crick_Institute
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gptkbp:awards
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gptkb:Nobel_Prize_in_Physiology_or_Medicine
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gptkbp:birthDate
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1954-05-14
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gptkbp:birthPlace
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gptkb:Northampton,_England
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gptkbp:children
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2
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gptkbp:community
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Hypoxia_and_Cancer_Group
Metabolism_and_Cancer_Group
|
gptkbp:education
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gptkb:University_of_Cambridge
gptkb:University_of_Oxford
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gptkbp:fellowship
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gptkb:American_Academy_of_Arts_and_Sciences
gptkb:Academy_of_Medical_Sciences
gptkb:European_Molecular_Biology_Organization
gptkb:Royal_Society
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gptkbp:field
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medicine
physiology
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https://www.w3.org/2000/01/rdf-schema#label
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Peter Ratcliffe
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gptkbp:influencedBy
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gptkb:Francis_Crick
gptkb:David_Baltimore
gptkb:James_Watson
gptkb:Harold_Varmus
|
gptkbp:influences
|
gptkb:Sir_John_Gurdon
gptkb:William_Kaelin_Jr.
gptkb:Gregg_Semenza
gptkb:Sir_Peter_Ratcliffe
|
gptkbp:knownFor
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research in cellular oxygen sensing
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gptkbp:notableFeature
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gptkb:Sir_John_Gurdon
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gptkbp:notableWork
|
Mechanisms of hypoxia-induced gene expression
Metabolic adaptation to hypoxia
Oxygen sensing and signaling pathways
Role of HIF in cancer progression
HIF-1_and_HIF-2_in_oxygen_sensing
HIF_and_aging
HIF_and_cardiovascular_disease
HIF_and_clinical_applications
HIF_and_drug_development
HIF_and_immune_response
HIF_and_inflammation
HIF_and_metabolic_reprogramming
HIF_and_neurodegeneration
HIF_and_stem_cell_biology
HIF_and_therapeutic_resistance
HIF_and_tumor_microenvironment
Therapeutic_targeting_of_HIF_pathways
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gptkbp:researchContribution
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understanding of cancer biology
insights into metabolic diseases
discovery_of_the_role_of_HIF_in_oxygen_sensing
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gptkbp:researchFocus
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metabolism
hypoxia
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gptkbp:residence
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gptkb:Oxford,_England
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gptkbp:spouse
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gptkb:Dr._Anne_Ratcliffe
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gptkbp:website
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https://www.ox.ac.uk
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