Statements (37)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
muscle relaxant
quaternary ammonium compound neuromuscular-blocking drug |
| gptkbp:antidote |
gptkb:neostigmine
gptkb:sugammadex |
| gptkbp:approved_for_medical_use |
1974
|
| gptkbp:ATCCode |
M03AC01
|
| gptkbp:CASNumber |
15500-66-0
|
| gptkbp:chemicalFormula |
C35H60Br2N2O4
|
| gptkbp:contraindication |
gptkb:myasthenia_gravis
hypersensitivity to pancuronium |
| gptkbp:discoveredBy |
gptkb:Organon
|
| gptkbp:discoveredIn |
1964
|
| gptkbp:excretion |
kidneys
|
| https://www.w3.org/2000/01/rdf-schema#label |
Pancuronium bromide
|
| gptkbp:IUPACName |
(4aS,4bR,6aS,8aS,10aS,10bS,12aR)-1,1'-[(3,17-dioxo-2,16-dioxapentacyclo[10.7.1.0^{2,10}.0^{4,9}.0^{13,18}]nonadeca-4(9),5,7,13(18),14,16-hexaene-6a,12a-diyl)bis(oxy)]bis(1-methylpiperidinium) dibromide
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
blocks acetylcholine at neuromuscular junction
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
572.7 g/mol
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:proteinBinding |
87%
|
| gptkbp:PubChem_CID |
CHEMBL1201192
441304 DB01337 |
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
hypertension
tachycardia apnea increased salivation |
| gptkbp:UNII |
W9YXS298BM
|
| gptkbp:used_in |
lethal injection protocols
|
| gptkbp:usedFor |
mechanical ventilation
facilitation of endotracheal intubation muscle relaxation during surgery |
| gptkbp:bfsParent |
gptkb:Lethal_Injection
|
| gptkbp:bfsLayer |
6
|