Pancuronium bromide

URI: https://gptkb.org/entity/Pancuronium_bromide

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:muscle_relaxant gptkb:quaternary_ammonium_compound gptkb:neuromuscular-blocking_drug
gptkbp:antidote	gptkb:neostigmine gptkb:sugammadex
gptkbp:approved_for_medical_use	1974
gptkbp:ATCCode	M03AC01
gptkbp:CASNumber	15500-66-0
gptkbp:chemicalFormula	C35H60Br2N2O4
gptkbp:contraindication	gptkb:myasthenia_gravis hypersensitivity to pancuronium
gptkbp:discoveredBy	gptkb:Organon
gptkbp:discoveredIn	1964
gptkbp:excretion	kidneys
gptkbp:IUPACName	(4aS,4bR,6aS,8aS,10aS,10bS,12aR)-1,1'-[(3,17-dioxo-2,16-dioxapentacyclo[10.7.1.0^{2,10}.0^{4,9}.0^{13,18}]nonadeca-4(9),5,7,13(18),14,16-hexaene-6a,12a-diyl)bis(oxy)]bis(1-methylpiperidinium) dibromide
gptkbp:legalStatus	prescription only
gptkbp:mechanismOfAction	blocks acetylcholine at neuromuscular junction
gptkbp:metabolism	liver
gptkbp:molecularWeight	572.7 g/mol
gptkbp:pregnancyCategory	C (US)
gptkbp:proteinBinding	87%
gptkbp:PubChem_CID	CHEMBL1201192 441304 DB01337
gptkbp:routeOfAdministration	intravenous
gptkbp:sideEffect	hypertension tachycardia apnea increased salivation
gptkbp:UNII	W9YXS298BM
gptkbp:used_in	lethal injection protocols
gptkbp:usedFor	mechanical ventilation facilitation of endotracheal intubation muscle relaxation during surgery
gptkbp:bfsParent	gptkb:Lethal_Injection
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Pancuronium bromide