Pan-cancer analysis of whole genomes
GPTKB entity
Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:scientific_research
|
| gptkbp:analyzes |
2,658 cancer whole genomes
38 tumor types |
| gptkbp:author |
gptkb:Steven_L._Salzberg
gptkb:Serena_Nik-Zainal gptkb:Gad_Getz David W. Y. Tsui Iñigo Martincorena Jan O. Korbel Lincoln D. Stein Michael R. Stratton Moritz Gerstung PCAWG Consortium Peter J. Campbell Peter J. Park |
| gptkbp:doi |
10.1038/s41586-020-1969-6
|
| gptkbp:foundIn |
genomic instability
tumor microenvironment driver mutations mutational signatures non-coding mutations germline variants structural variation copy number alterations tumor evolution genomic rearrangements cancer cell-of-origin cancer driver genes cancer heterogeneity chromothripsis clonal evolution epigenetic alterations immune infiltration mobile element insertions mutational burden mutational clonality mutational landscape mutational processes mutational timing non-coding regulatory elements telomere maintenance mechanisms transcriptional consequences tumor purity viral integrations |
| gptkbp:partOf |
PCAWG (Pan-Cancer Analysis of Whole Genomes)
|
| gptkbp:publicationDate |
2020-02-05
|
| gptkbp:publishedIn |
gptkb:Nature
|
| gptkbp:topic |
tumor biology
cancer genomics whole genome sequencing |
| gptkbp:bfsParent |
gptkb:Nature_2020_Pan-Cancer_Analysis_papers
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Pan-cancer analysis of whole genomes
|