Pac Bio sequencing platforms
GPTKB entity
Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DJ
|
| gptkbp:allows |
higher error rates compared to short reads
higher initial investment cost longer run times |
| gptkbp:analysis |
can be integrated with other sequencing data
requires specialized bioinformatics tools |
| gptkbp:application |
genomics
transcriptomics metagenomics |
| gptkbp:benefits |
detection of structural variants
improved assembly of complex genomes phasing of haplotypes |
| gptkbp:collaborations |
various academic institutions
genomic research projects |
| gptkbp:competitors |
gptkb:Oxford_Nanopore_Technologies
Illumina sequencing |
| gptkbp:data_type |
BAM and FASTQ
|
| gptkbp:developed_by |
gptkb:Pacific_Biosciences
|
| gptkbp:features |
high throughput
real-time sequencing low bias no amplification required |
| gptkbp:first_introduced |
gptkb:2011
|
| https://www.w3.org/2000/01/rdf-schema#label |
Pac Bio sequencing platforms
|
| gptkbp:impact |
advancements in personalized medicine
understanding of genetic diseases contributions to evolutionary biology insights into microbial diversity facilitation of synthetic biology research |
| gptkbp:input_output |
long reads up to 30 kb or more
up to 1.5 million reads per SMRT Cell |
| gptkbp:known_for |
long-read sequencing
|
| gptkbp:part_of |
next-generation sequencing (NGS)
|
| gptkbp:performance |
high accuracy with circular consensus sequencing (CCS)
|
| gptkbp:platform |
gptkb:Sequel_II_System
RSII Sequel System |
| gptkbp:project |
improvements in accuracy
enhancements in throughput integration with AI for data analysis new applications in clinical genomics |
| gptkbp:seed_dispersal |
variable depending on application
cost-effective for large genomes |
| gptkbp:technology |
gptkb:SMRT_Cell
SMRT Link software |
| gptkbp:user_base |
environmental scientists
agricultural scientists clinical researchers researchers in genomics |
| gptkbp:uses |
gptkb:Single_Molecule,_Real-Time_(SMRT)_sequencing
|
| gptkbp:bfsParent |
gptkb:Pac_Bio_Sequel_System
|
| gptkbp:bfsLayer |
6
|