|
gptkbp:instance_of
|
gptkb:legal_case
|
|
gptkbp:clinical_trial
|
gptkb:sacubitril/valsartan
|
|
gptkbp:community_impact
|
gptkb:battle
|
|
gptkbp:completed
|
gptkb:2014
|
|
gptkbp:complications
|
gptkb:battle
|
|
gptkbp:conducted
|
gptkb:Europe
gptkb:Asia
gptkb:North_America
clinical research organizations
|
|
gptkbp:contributed_to
|
ARNI therapy
|
|
gptkbp:design
|
gptkb:battle
|
|
gptkbp:focuses_on
|
heart failure
|
|
gptkbp:has_backstory
|
gptkb:battle
|
|
gptkbp:has_impact_on
|
heart failure treatment guidelines
|
|
gptkbp:has_influence_on
|
gptkb:battle
|
|
gptkbp:healthcare
|
18 years and older
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PARADIGM-HF trial
|
|
gptkbp:improves
|
quality of life
|
|
gptkbp:influenced_by
|
gptkb:battle
heart failure management
|
|
gptkbp:is_a_center_for
|
gptkb:battle
|
|
gptkbp:is_associated_with
|
gptkb:sacubitril/valsartan
|
|
gptkbp:is_cited_in
|
numerous studies
|
|
gptkbp:is_compared_to
|
sacubitril/valsartan and enalapril
|
|
gptkbp:is_part_of
|
larger research initiatives
heart failure research history
|
|
gptkbp:is_recognized_by
|
landmark trial
|
|
gptkbp:is_referenced_in
|
subsequent trials
|
|
gptkbp:launched
|
gptkb:2011
|
|
gptkbp:location
|
multiple countries
|
|
gptkbp:moral
|
gptkb:battle
|
|
gptkbp:notable_work
|
gptkb:battle
|
|
gptkbp:participants
|
hospitalization for heart failure
cardiovascular death
|
|
gptkbp:presented_by
|
conferences
|
|
gptkbp:provides_information_on
|
safety and efficacy
|
|
gptkbp:publishes
|
gptkb:battle
|
|
gptkbp:reduces
|
hospitalizations
|
|
gptkbp:registration
|
clinicaltrials.gov
|
|
gptkbp:research
|
gptkb:battle
|
|
gptkbp:result
|
gptkb:New_England_Journal_of_Medicine
gptkb:2014
|
|
gptkbp:sponsor
|
gptkb:Novartis
|
|
gptkbp:student_enrollment
|
8442 patients
|
|
gptkbp:succeeded_by
|
gptkb:Entresto
|
|
gptkbp:treatment
|
gptkb:battle
reduced ejection fraction
|
|
gptkbp:vision
|
gptkb:battle
|
|
gptkbp:bfsParent
|
gptkb:Dr._Milton_Packer
|
|
gptkbp:bfsLayer
|
6
|