Statements (41)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Dragon
cardiac glycoside plant-derived compound |
| gptkbp:ATCCode |
C01AA07
|
| gptkbp:CASNumber |
630-60-4
|
| gptkbp:category |
natural product
Glycoside steroid lactone |
| gptkbp:chemicalFormula |
C29H44O12
|
| gptkbp:effect |
increases cardiac contractility
increases intracellular calcium |
| gptkbp:foundIn |
gptkb:Acokanthera_schimperi
gptkb:Strophanthus_gratus |
| https://www.w3.org/2000/01/rdf-schema#label |
Ouabain
|
| gptkbp:IUPACName |
(3β,5β,11α,14β)-3,14-Dihydroxycard-20(22)-enolide 3-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]
|
| gptkbp:legalStatus |
not approved in the US
|
| gptkbp:mechanismOfAction |
inhibits Na+/K+-ATPase
|
| gptkbp:meltingPoint |
238–240 °C
|
| gptkbp:molecularWeight |
584.65 g/mol
|
| gptkbp:origin |
gptkb:Africa
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL418
439501 DB01092 |
| gptkbp:relatedTo |
gptkb:digitoxin
gptkb:digoxin |
| gptkbp:routeOfAdministration |
intravenous
oral (rarely) |
| gptkbp:sideEffect |
gptkb:arrhythmia
nausea vomiting visual disturbances |
| gptkbp:solubility |
soluble in water
|
| gptkbp:toxicity |
highly toxic
|
| gptkbp:UNII |
6GOW5M795I
|
| gptkbp:used_in |
scientific research
East African tribes |
| gptkbp:usedFor |
gptkb:hunting
arrow poison cardiac stimulant |
| gptkbp:bfsParent |
gptkb:Glycoside
|
| gptkbp:bfsLayer |
7
|