Ouabain

URI: https://gptkb.org/entity/Ouabain

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:cardiac_glycoside gptkb:plant-derived_compound gptkb:Dragon
gptkbp:ATCCode	C01AA07
gptkbp:CASNumber	630-60-4
gptkbp:category	gptkb:natural_product gptkb:Glycoside steroid lactone
gptkbp:chemicalFormula	C29H44O12
gptkbp:effect	increases cardiac contractility increases intracellular calcium
gptkbp:foundIn	gptkb:Acokanthera_schimperi gptkb:Strophanthus_gratus
gptkbp:IUPACName	(3β,5β,11α,14β)-3,14-Dihydroxycard-20(22)-enolide 3-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]
gptkbp:legalStatus	not approved in the US
gptkbp:mechanismOfAction	inhibits Na+/K+-ATPase
gptkbp:meltingPoint	238–240 °C
gptkbp:molecularWeight	584.65 g/mol
gptkbp:origin	gptkb:Africa
gptkbp:PubChem_CID	gptkb:CHEMBL418 439501 DB01092
gptkbp:relatedTo	gptkb:digitoxin gptkb:digoxin
gptkbp:routeOfAdministration	intravenous oral (rarely)
gptkbp:sideEffect	gptkb:arrhythmia nausea vomiting visual disturbances
gptkbp:solubility	soluble in water
gptkbp:toxicity	highly toxic
gptkbp:UNII	6GOW5M795I
gptkbp:used_in	gptkb:scientific_research East African tribes
gptkbp:usedFor	gptkb:hunting arrow poison cardiac stimulant
http://www.w3.org/2000/01/rdf-schema#label	Ouabain