Orfadin

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:activeIngredient nitisinone
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
2002
gptkbp:ATCCode A16AX04
gptkbp:CASNumber 104206-65-7
gptkbp:chemicalFormula C14H10F3NO5S
gptkbp:form capsule
oral suspension
https://www.w3.org/2000/01/rdf-schema#label Orfadin
gptkbp:KEGGID D08213
gptkbp:legalStatus prescription only
gptkbp:manufacturer Swedish Orphan Biovitrum
gptkbp:mechanismOfAction 4-hydroxyphenylpyruvate dioxygenase inhibitor
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID 4464
DB00661
gptkbp:routeOfAdministration oral
gptkbp:sideEffect thrombocytopenia
leukopenia
photophobia
keratitis
ocular symptoms
gptkbp:UNII 8ECV5P0K1J
gptkbp:usedFor hereditary tyrosinemia type 1
gptkbp:bfsParent gptkb:Sobi
gptkbp:bfsLayer 7