Oligodendrocytes

GPTKB entity

Statements (63)
Predicate Object
gptkbp:instance_of gptkb:Cell
gptkbp:are_derived_from Oligodendrocyte precursor cells (OPCs)
gptkbp:are_part_of White matter in the brain
Nervous system support cells
gptkbp:associated_with Multiple sclerosis
gptkbp:can_be_regenerated_by Stem cell therapy
gptkbp:can_create Proteins like MBP (Myelin Basic Protein)
gptkbp:defeated Neurodegenerative diseases
gptkbp:developed_by Neural stem cells
gptkbp:function Myelinate axons in the central nervous system
gptkbp:has_role Cognitive functions
https://www.w3.org/2000/01/rdf-schema#label Oligodendrocytes
gptkbp:importance Support neuronal function
gptkbp:influence Nerve signal transmission
Axonal health
gptkbp:interacts_with gptkb:Brain
gptkbp:involved_in CNS repair mechanisms
gptkbp:is_affected_by Infections
Inflammation
Oxidative stress
Genetic mutations
Toxins
Chronic stress
Age-related changes
gptkbp:is_critical_for Neuronal communication
Maintaining axonal integrity
gptkbp:is_essential_for Rapid signal conduction
Neuronal survival
CNS homeostasis
Neuronal plasticity
Proper neuronal signaling
gptkbp:is_found_in Brain and spinal cord
gptkbp:is_influenced_by Environmental factors
Dietary factors
gptkbp:is_involved_in Synaptic plasticity
Cell signaling pathways
Neuroprotection
Neurotransmitter regulation
Neurodevelopmental processes
Axonal regeneration
Myelin repair processes
Neuroinflammatory responses
gptkbp:is_linked_to Learning and memory
Neurodegeneration
gptkbp:is_recognized_by Specific markers like Olig2
gptkbp:is_studied_in Clinical trials
Imaging techniques
Genetic analysis
Animal models
Neuroscience research
Cell culture techniques
Post-mortem brain tissue
gptkbp:is_targeted_at Therapeutic interventions
Neuroprotective agents
gptkbp:location Central nervous system
gptkbp:number Can myelinate multiple axons
gptkbp:produces Myelin sheath
gptkbp:regenerate Myelin after injury
gptkbp:responds_to Neurotrophic factors
gptkbp:role Insulation of axons
gptkbp:type Type of glial cell
gptkbp:bfsParent gptkb:Brain
gptkbp:bfsLayer 4