Statements (62)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:activities |
provides passive immunity
|
| gptkbp:appointed_by |
intravenous infusion
|
| gptkbp:approves |
gptkb:2000
gptkb:FDA |
| gptkbp:clinical_trial |
Phase III
immunomodulation studies on efficacy studies on safety replacement therapy studies on dosing |
| gptkbp:compression_ratio |
varies by patient
|
| gptkbp:contains |
human immunoglobulin G (Ig G)
|
| gptkbp:contraindication |
hypersensitivity to immunoglobulin products
|
| gptkbp:dosage_form |
solution for infusion
|
| gptkbp:education |
recognize signs of allergic reactions
reporting side effects importance of hydration during infusion |
| gptkbp:formulation |
sterile solution
|
| gptkbp:has_expansion |
isotonic
|
| https://www.w3.org/2000/01/rdf-schema#label |
Octagam
|
| gptkbp:indication |
treatment of chronic inflammatory demyelinating polyneuropathy (CIDP)
|
| gptkbp:ingredients |
immunoglobulin G
|
| gptkbp:interacts_with |
live vaccines
other immunosuppressants |
| gptkbp:is_available_in |
various concentrations
|
| gptkbp:is_monitored_by |
thromboembolic events
renal function hemoglobin levels |
| gptkbp:is_used_for |
treatment of primary immunodeficiency
|
| gptkbp:level |
6.0 to 7.0
|
| gptkbp:manager |
IV
|
| gptkbp:manufacturer |
gptkb:Octapharma
|
| gptkbp:marketed_as |
multiple countries
|
| gptkbp:packaging |
vials
|
| gptkbp:pharmacokinetics |
half-life of 21 days
|
| gptkbp:population |
adults and children
|
| gptkbp:provides_information_on |
IVIG therapy guidelines
|
| gptkbp:regulatory_compliance |
approved for use in Europe
approved for use in the US approved for use in Australia approved for use in Canada |
| gptkbp:research_focus |
autoimmune diseases
infectious diseases immunology |
| gptkbp:shelf_life |
24 months
|
| gptkbp:side_effect |
fatigue
headache nausea fever chills thrombosis anaphylaxis hemolysis renal dysfunction aseptic meningitis |
| gptkbp:storage |
refrigerated
|
| gptkbp:supply_chain |
cold chain logistics
availability in pharmacies distribution to hospitals |
| gptkbp:bfsParent |
gptkb:Octapharma
|
| gptkbp:bfsLayer |
8
|