O'Brien-Fleming Method

GPTKB entity

Statements (16)
Predicate Object
gptkbp:instanceOf statistical analysis
gptkbp:appliesTo randomized controlled trials
gptkbp:citation Biometrics 1979; 35(3): 549-556
gptkbp:developedBy gptkb:David_O'Brien
Thomas R. Fleming
gptkbp:feature alpha spending function
conservative early stopping boundaries
controls type I error
https://www.w3.org/2000/01/rdf-schema#label O'Brien-Fleming Method
gptkbp:introducedIn 1979
gptkbp:purpose group sequential design
interim analysis
gptkbp:relatedTo Pocock method
gptkbp:usedIn clinical trials
gptkbp:bfsParent gptkb:Group_Sequential_Methods
gptkbp:bfsLayer 8