NT-proBNP

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf biomarker
gptkbp:alternativeName N-terminal prohormone of brain natriuretic peptide
gptkbp:approvedBy gptkb:FDA
gptkbp:degradedBy neutral endopeptidase
gptkbp:discoveredIn 1990s
gptkbp:elevatedIn heart failure
renal failure
pulmonary embolism
gptkbp:fullName N-terminal pro b-type natriuretic peptide
gptkbp:halfLife 60-120 minutes
https://www.w3.org/2000/01/rdf-schema#label NT-proBNP
gptkbp:measures blood
gptkbp:molecularWeight 8.5 kDa
gptkbp:producedBy cardiac ventricles
gptkbp:range <125 pg/mL (under 75 years)
<450 pg/mL (over 75 years)
gptkbp:relatedTo gptkb:BNP
gptkbp:releasedInResponseTo ventricular stretch
gptkbp:type immunoassay
gptkbp:usedFor risk stratification in acute coronary syndrome
diagnosis of heart failure
monitoring therapy in heart failure
prognosis in cardiovascular disease
gptkbp:bfsParent gptkb:ATTR_amyloidosis
gptkbp:bfsLayer 8