MutSig algorithm

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf bioinformatics algorithm
gptkbp:analyzes somatic mutation data
gptkbp:citation Lawrence MS et al., Nature 2013
gptkbp:considers background mutation rate
gene-specific mutation rates
mutation clustering
mutation context
gptkbp:developedBy gptkb:Broad_Institute
gptkbp:firstPublished 2010
https://www.w3.org/2000/01/rdf-schema#label MutSig algorithm
gptkbp:input mutation data from sequencing studies
gptkbp:notableRelease MutSig2.0
MutSigCV
gptkbp:output list of significantly mutated genes
gptkbp:publishedIn gptkb:Nature
gptkbp:relatedTo genomic data analysis
Cancer Genome Atlas (TCGA)
gptkbp:usedFor identifying significantly mutated genes in cancer
gptkbp:usedIn cancer genomics
gptkbp:website https://www.broadinstitute.org/cancer/cga/mutsig
gptkbp:bfsParent gptkb:Gad_Getz
gptkbp:bfsLayer 7