Mannitol

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instanceOf sugar alcohol
gptkbp:appearance white crystalline solid
gptkbp:ATCCode A06AD16
B05BC01
gptkbp:boilingPoint none (decomposes)
gptkbp:CASNumber 69-65-8
gptkbp:category gptkb:food
diuretic
polyol
gptkbp:chemicalFormula C6H14O6
gptkbp:contraindication anuria
active intracranial bleeding
severe dehydration
gptkbp:density 1.52 g/cm³
gptkbp:discoveredBy gptkb:Joseph_Louis_Proust
gptkbp:discoveredIn 1806
gptkbp:E-Number E421
gptkbp:energyEfficiency 1.6 kcal/g
gptkbp:excretion renal
gptkbp:flavor gptkb:sugar
gptkbp:foundIn gptkb:algae
fungi
plants
https://www.w3.org/2000/01/rdf-schema#label Mannitol
gptkbp:isomerOf galactitol
sorbitol
gptkbp:IUPACName (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
gptkbp:KEGGID D01836
gptkbp:legalStatus OTC (over-the-counter)
gptkbp:meltingPoint 165-170 °C
gptkbp:MeSH_ID D008345
gptkbp:metabolism not significantly metabolized
gptkbp:molecularWeight 182.17 g/mol
gptkbp:PubChem_CID 6251
CHEBI:16899
CHEMBL1201191
DB00742
gptkbp:routeOfAdministration oral
intravenous
gptkbp:sideEffect diarrhea
electrolyte imbalance
gptkbp:solubility 216 g/L (25 °C)
gptkbp:toxicity low
gptkbp:UNII 3OWL53L36A
gptkbp:usedFor promote diuresis
reduce intracranial pressure
reduce intraocular pressure
renal protection during surgery
gptkbp:uses gptkb:sugar
pharmaceutical excipient
osmotic diuretic
renal diagnostic aid
gptkbp:bfsParent gptkb:Bladderwrack
gptkbp:bfsLayer 7