Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
natural product synthesis
pharmaceutical synthesis |
| gptkbp:category |
carbon-carbon bond forming reaction
multicomponent reaction |
| gptkbp:firstReported |
1912
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mannich reaction
|
| gptkbp:involves |
amphetamine
aldehyde ketone |
| gptkbp:mechanismOfAction |
nucleophilic addition
|
| gptkbp:namedAfter |
gptkb:Carl_Mannich
|
| gptkbp:product |
beta-amino carbonyl compound
|
| gptkbp:relatedTo |
gptkb:aldol_reaction
enamine chemistry |
| gptkbp:requires |
acidic or neutral conditions
|
| gptkbp:type |
condensation reaction
|
| gptkbp:usedIn |
organic synthesis
|
| gptkbp:yield |
beta-amino aldehyde
beta-amino ketone |
| gptkbp:bfsParent |
gptkb:Organic_Chemistry
|
| gptkbp:bfsLayer |
6
|