|
gptkbp:instance_of
|
gptkb:vaccine
|
|
gptkbp:accessories
|
yes
|
|
gptkbp:administered_by
|
gptkb:children
|
|
gptkbp:approves
|
gptkb:2021
gptkb:European_Union
|
|
gptkbp:clinical_trial
|
over 15,000
Phase 3
|
|
gptkbp:clinical_trials_end_date
|
gptkb:2019
|
|
gptkbp:clinical_trials_location
|
gptkb:Africa
|
|
gptkbp:clinical_trials_start_date
|
gptkb:2014
|
|
gptkbp:community_impact
|
reduces malaria cases
reduces malaria deaths
|
|
gptkbp:cost_per_dose
|
approximately $5
|
|
gptkbp:defense
|
yes
|
|
gptkbp:developed_by
|
gptkb:Glaxo_Smith_Kline
|
|
gptkbp:distribution
|
gptkb:sub-Saharan_Africa
|
|
gptkbp:funding
|
millions of dollars
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Malaria vaccine
|
|
gptkbp:is_effective_against
|
approximately 30%
|
|
gptkbp:is_funded_by
|
PATH Malaria Vaccine Initiative
|
|
gptkbp:is_vulnerable_to
|
yes
over 30 years
post-marketing surveillance
ongoing campaigns
subunit vaccine
4 doses
|
|
gptkbp:mechanism_of_action
|
prevention of malaria infection
|
|
gptkbp:partnerships
|
gptkb:Global_Fund
gptkb:Bill_&_Melinda_Gates_Foundation
gptkb:Gavi,_the_Vaccine_Alliance
|
|
gptkbp:public_health_importance
|
yes
|
|
gptkbp:requires_boosters
|
yes
|
|
gptkbp:research_institutes
|
gptkb:University_of_Oxford
gptkb:Walter_Reed_Army_Institute_of_Research
gptkb:University_of_Ghana
|
|
gptkbp:side_effect
|
fatigue
headache
fever
pain at injection site
|
|
gptkbp:storage
|
refrigerated
|
|
gptkbp:target_audience
|
children under 5
|
|
gptkbp:targets
|
malaria
|
|
gptkbp:type
|
RTS, S/ AS01
|
|
gptkbp:vaccine_administration_route
|
intramuscular
|
|
gptkbp:vaccine_community_acceptance
|
varies by region
|
|
gptkbp:vaccine_efficacy_duration
|
up to 4 years
|
|
gptkbp:vaccine_impact_on_health_systems
|
requires infrastructure improvements
requires training of healthcare workers
requires public education
|
|
gptkbp:vaccine_research_focus
|
improving efficacy
reducing side effects
combination with other vaccines
expanding age range
|
|
gptkbp:vaccine_storage_temperature
|
2-8° C
|
|
gptkbp:whoapproval_date
|
October 2021
|
|
gptkbp:bfsParent
|
gptkb:Crucell
|
|
gptkbp:bfsLayer
|
5
|