Major Depressive Disorder

GPTKB entity

Statements (62)
Predicate Object
gptkbp:instanceOf mental disorder
gptkbp:affects gptkb:Animalia
cognition
mood
physical health
gptkbp:alsoKnownAs clinical depression
major depression
gptkbp:characterizedBy fatigue
sleep disturbances
suicidal thoughts
loss of interest
changes in appetite
feelings of worthlessness
impaired concentration
persistent low mood
gptkbp:class mood disorder
gptkbp:comorbidity substance use disorders
anxiety disorders
personality disorders
chronic medical conditions
gptkbp:complication suicide
substance abuse
occupational impairment
impaired social functioning
gptkbp:diagnosedBy gptkb:DSM-5_criteria
clinical interview
gptkbp:differentialDiagnosis gptkb:adjustment_disorder
bipolar disorder
grief
dysthymia
gptkbp:DSM-5_code 296.2
296.3
gptkbp:firstDescribed gptkb:Emil_Kraepelin
https://www.w3.org/2000/01/rdf-schema#label Major Depressive Disorder
gptkbp:ICD-10_code gptkb:F32
gptkb:F33
gptkbp:onset can occur at any age
most common in 20s and 30s
gptkbp:prevalence more common in women
common worldwide
gptkbp:prognosis variable
can be chronic
can be recurrent
gptkbp:riskFactor gptkb:trauma
chronic illness
substance abuse
chronic stress
family history of depression
gptkbp:subspecies single episode
recurrent episode
gptkbp:symptom gptkb:anhedonia
guilt
hopelessness
psychomotor agitation
psychomotor retardation
gptkbp:treatment gptkb:psychotherapy
cognitive behavioral therapy
electroconvulsive therapy
antidepressant medication
gptkbp:bfsParent gptkb:Bipolar_I_Disorder
gptkb:MDD
gptkbp:bfsLayer 6