Statements (70)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic alteration
|
| gptkbp:associated_with |
cell cycle dysregulation
specific mutations increased angiogenesis increased metastasis poor survival rates specific histological features activation of downstream signaling altered tumor metabolism |
| gptkbp:associatedWith |
cancer
|
| gptkbp:can_be |
chromosomal alterations
resistance to targeted therapies response to therapy |
| gptkbp:community_service |
treatment response
|
| gptkbp:has_a_focus_on |
oncology
cancer research therapeutic development |
| gptkbp:has_partnerships_with |
clinical outcomes
|
| https://www.w3.org/2000/01/rdf-schema#label |
MET amplification
|
| gptkbp:impact |
patient outcomes
|
| gptkbp:influence |
therapeutic strategies
treatment decisions |
| gptkbp:is_a_key_component_of |
molecular diagnostics
|
| gptkbp:is_a_source_of |
tumorigenesis
|
| gptkbp:is_a_subject_of |
biomedical studies
molecular characterization |
| gptkbp:is_a_symbol_of |
treatment outcomes
tumor aggressiveness aggressive disease |
| gptkbp:is_aimed_at |
combination therapies
MET_inhibitors |
| gptkbp:is_available_in |
non-small cell lung cancer
various tumor types |
| gptkbp:is_characterized_by |
gene copy number increase
|
| gptkbp:is_evaluated_by |
next-generation sequencing
molecular profiling |
| gptkbp:is_featured_in |
hepatocellular carcinoma
|
| gptkbp:is_involved_in |
cell signaling pathways
tumor heterogeneity cell survival pathways drug resistance mechanisms tumor evolution |
| gptkbp:is_linked_to |
cell motility
poor prognosis immune evasion invasive behavior of tumors |
| gptkbp:is_recognized_for |
biopsy samples
PCR_techniques |
| gptkbp:is_referenced_in |
precision oncology
|
| gptkbp:is_studied_in |
clinical trials
tumor microenvironment retrospective studies tumor biology tumor samples preclinical models |
| gptkbp:leads |
tumor progression
enhanced cell proliferation |
| gptkbp:occursAnnually |
gastric cancer
|
| gptkbp:related_to |
personalized medicine
epithelial-mesenchymal transition clinical trial eligibility |
| gptkbp:targets |
immunotherapy
therapeutic intervention |
| gptkbp:updates |
MET_protein_expression
|
| gptkbp:visitedBy |
genetic testing
circulating tumor DNA |
| gptkbp:was_a_factor_in |
treatment planning
treatment resistance cancer progression. |
| gptkbp:was_a_result_of |
gene rearrangements
|