Statements (75)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gene
|
gptkbp:associatedWith |
gptkb:Huntington's_disease
Parkinson's disease cognitive decline cognitive function neuroinflammation traumatic brain injury multiple sclerosis epilepsy mood disorders neuronal development brain development cognitive impairment neurodevelopmental disorders autism spectrum disorders neuropsychiatric disorders mental retardation schizophrenia risk |
gptkbp:bornIn |
neurons
|
gptkbp:breedingSeason |
protein-coding gene
|
gptkbp:clinicalTrials |
biomarker for neurological diseases
|
gptkbp:code |
MAP1B_protein
|
gptkbp:community |
developmental stages
|
gptkbp:culturalEvents |
mouse
|
gptkbp:diseaseResistance |
gptkb:schizophrenia
|
gptkbp:function |
cytoskeletal organization
|
gptkbp:geneticDiversity |
gptkb:MAP1B
neurodegenerative disorders 2q35 microtubule-associated proteins |
https://www.w3.org/2000/01/rdf-schema#label |
MAP1B gene
|
gptkbp:influences |
cell proliferation
cell signaling pathways cell survival synaptic plasticity synaptic function neurite outgrowth neuronal survival learning and memory cell fate determination axon growth |
gptkbp:interactsWith |
tau protein
|
gptkbp:involvedIn |
cell differentiation
cell signaling neurotransmitter release neurogenesis neuroprotection cell adhesion cell migration axon regeneration neural repair axon stability axon transport microtubule assembly synaptic development |
gptkbp:is_a_route_for |
axon guidance
|
gptkbp:is_evaluated_by |
brain
|
gptkbp:isActiveIn |
GSK-3β
|
gptkbp:linkedTo |
mental health disorders
neuroplasticity neurodegeneration cognitive disorders brain tumors spinal cord injury brain injury recovery cerebral ischemia neurodegenerative processes neurodevelopmental pathways |
gptkbp:locatedIn |
human chromosome 2
|
gptkbp:regulatoryBody |
neurotrophic factors
|
gptkbp:regulatoryCompliance |
stabilizing microtubules
|
gptkbp:relatedTo |
Alzheimer's disease
|
gptkbp:research |
animal models
|
gptkbp:researchFocus |
neurobiology
|
gptkbp:researchInterest |
gene therapy
|