Liquid Chromatography-Mass Spectrometry
GPTKB entity
Statements (51)
Predicate | Object |
---|---|
gptkbp:instanceOf |
analytical technique
|
gptkbp:abbreviation |
gptkb:LC-MS
|
gptkbp:advantage |
high sensitivity
high specificity ability to analyze complex mixtures |
gptkbp:can_analyze |
non-volatile compounds
polar compounds thermally labile compounds |
gptkbp:can_be_automated |
true
|
gptkbp:can_be_coupled_with |
high-resolution mass spectrometry
tandem mass spectrometry (MS/MS) |
gptkbp:canBe |
toxicology
biomarker discovery drug metabolism studies |
gptkbp:combines |
mass spectrometry
liquid chromatography |
gptkbp:component |
spectrometer
interface liquid chromatograph |
gptkbp:detects |
small molecules
large biomolecules |
gptkbp:developedBy |
1970s
|
https://www.w3.org/2000/01/rdf-schema#label |
Liquid Chromatography-Mass Spectrometry
|
gptkbp:interface |
electrospray ionization
atmospheric pressure chemical ionization matrix-assisted laser desorption/ionization |
gptkbp:limitation |
matrix effects
instrument cost |
gptkbp:output |
chromatogram
mass spectrum |
gptkbp:requires |
maintenance
calibration sample preparation |
gptkbp:used_in |
metabolomics
proteomics food safety testing analytical chemists environmental analysis pharmaceutical analysis environmental scientists biochemists food scientists pharmaceutical scientists |
gptkbp:usedFor |
chemical analysis
identification of compounds quantification of compounds |
gptkbp:相关技术 |
tandem mass spectrometry
gas chromatography-mass spectrometry ultra-high-performance liquid chromatography-mass spectrometry |
gptkbp:bfsParent |
gptkb:Ion_Mass_Spectrometer
|
gptkbp:bfsLayer |
7
|