Liquid Chromatography-Mass Spectrometry
GPTKB entity
Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:analytical_technique
|
| gptkbp:abbreviation |
gptkb:LC-MS
|
| gptkbp:advantage |
high sensitivity
high specificity ability to analyze complex mixtures |
| gptkbp:can_analyze |
non-volatile compounds
polar compounds thermally labile compounds |
| gptkbp:can_be_automated |
true
|
| gptkbp:can_be_coupled_with |
high-resolution mass spectrometry
tandem mass spectrometry (MS/MS) |
| gptkbp:canBe |
toxicology
biomarker discovery drug metabolism studies |
| gptkbp:combines |
mass spectrometry
liquid chromatography |
| gptkbp:component |
gptkb:interface
gptkb:spectrometer liquid chromatograph |
| gptkbp:detects |
small molecules
large biomolecules |
| gptkbp:developedBy |
1970s
|
| gptkbp:interface |
electrospray ionization
atmospheric pressure chemical ionization matrix-assisted laser desorption/ionization |
| gptkbp:limitation |
matrix effects
instrument cost |
| gptkbp:output |
chromatogram
mass spectrum |
| gptkbp:requires |
maintenance
calibration sample preparation |
| gptkbp:used_in |
metabolomics
proteomics food safety testing analytical chemists environmental analysis pharmaceutical analysis environmental scientists biochemists food scientists pharmaceutical scientists |
| gptkbp:usedFor |
chemical analysis
identification of compounds quantification of compounds |
| gptkbp:相关技术 |
tandem mass spectrometry
gas chromatography-mass spectrometry ultra-high-performance liquid chromatography-mass spectrometry |
| gptkbp:bfsParent |
gptkb:Ion_Mass_Spectrometer
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Liquid Chromatography-Mass Spectrometry
|