Properties (55)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cancer
|
| gptkbp:aftermath |
rare
|
| gptkbp:age |
adults
|
| gptkbp:associated_with |
gptkb:lipoma
other sarcomas |
| gptkbp:barrelLength |
depends on stage
higher in localized cases lower in metastatic cases |
| gptkbp:clinicalTrials |
ongoing
may metastasize to bones may metastasize to liver may metastasize to lungs |
| gptkbp:commonName |
adjuvant therapy
neoadjuvant_therapy |
| gptkbp:diseaseResistance |
imaging studies
biopsy varies by subtype |
| gptkbp:enrollment |
more common in males
average age of diagnosis is 50-60 years |
| gptkbp:geneticDiversity |
CDK4
TP53 MDM2 |
| gptkbp:historicalContext |
first described in 1871
|
| https://www.w3.org/2000/01/rdf-schema#label |
Liposarcoma
|
| gptkbp:impact |
surgery
radiation therapy chemotherapy |
| gptkbp:location |
abdominal cavity
limbs head and neck retroperitoneum |
| gptkbp:originatesFrom |
adipose tissue
|
| gptkbp:providesGuidelinesFor |
ESMO guidelines
NCCN_guidelines |
| gptkbp:research_areas |
gptkb:American_Cancer_Society
gptkb:National_Cancer_Institute |
| gptkbp:research_focus |
immunotherapy
targeted therapy molecular genetics |
| gptkbp:responseTime |
variable
|
| gptkbp:riskManagement |
obesity
radiation exposure genetic syndromes |
| gptkbp:runnerUp |
clinical evaluations
regular imaging |
| gptkbp:subclass |
dedifferentiated liposarcoma
myxoid liposarcoma pleomorphic liposarcoma well-differentiated liposarcoma |
| gptkbp:symptoms |
pain
swelling |
| gptkbp:type |
soft tissue sarcoma
|
| gptkbp:was_marked_by |
p53
p16 MDM2 amplification |