Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
synthetic progestogen |
| gptkbp:ATCCode |
G03AC03
|
| gptkbp:availableOn |
gptkb:tablet
implant IUD |
| gptkbp:CASNumber |
797-63-7
|
| gptkbp:component |
oral contraceptive pill
intrauterine device (IUD) |
| gptkbp:contraindication |
known or suspected pregnancy
unexplained vaginal bleeding hypersensitivity to levonorgestrel |
| gptkbp:discoveredBy |
gptkb:Schering_AG
|
| gptkbp:drugClass |
progestin
|
| gptkbp:eliminationHalfLife |
24 hours
|
| gptkbp:excretion |
urine
feces |
| gptkbp:hasMolecularFormula |
C21H28O2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Levonorgestrel
|
| gptkbp:interactsWith |
enzyme inducers (e.g., rifampicin, phenytoin)
|
| gptkbp:introducedIn |
1960s
|
| gptkbp:legalStatus |
off-patent
prescription only (most countries) over-the-counter (some countries) |
| gptkbp:mechanismOfAction |
alters cervical mucus
inhibits ovulation alters endometrial lining |
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
312.45 g/mol
|
| gptkbp:pregnancyCategory |
D
X Category X (contraindicated in pregnancy) |
| gptkbp:routeOfAdministration |
oral
intrauterine subdermal implant |
| gptkbp:sideEffect |
nausea
abdominal pain headache irregular menstrual bleeding |
| gptkbp:synonym |
LNG
NorLevo (brand name) Plan B (brand name) |
| gptkbp:usedFor |
oral contraceptive
treatment of heavy menstrual bleeding treatment of endometriosis hormonal contraception |
| gptkbp:WHOModelListOfEssentialMedicines |
included
|
| gptkbp:bfsParent |
gptkb:Emergency_Contraceptive_Pill
|
| gptkbp:bfsLayer |
7
|