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Lercanidipine
URI:
https://gptkb.org/entity/Lercanidipine
GPTKB entity
Statements (39)
Predicate
Object
gptkbp:instanceOf
gptkb:drug
beta blocker
gptkbp:approvalYear
1997
gptkbp:ATCCode
C08CA13
gptkbp:bioavailability
10%
gptkbp:CASNumber
100427-26-7
gptkbp:category
antihypertensive agent
gptkbp:chemicalClass
dihydropyridine
gptkbp:contraindication
pregnancy
severe liver impairment
gptkbp:discoveredBy
gptkb:Recordati
gptkbp:eliminationHalfLife
8-10 hours
gptkbp:excretion
urine
gptkbp:hasMolecularFormula
C36H41ClN2O6
https://www.w3.org/2000/01/rdf-schema#label
Lercanidipine
gptkbp:IUPACName
2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
gptkbp:KEGGID
D08144
gptkbp:legalStatus
prescription only
gptkbp:mechanismOfAction
blocks L-type calcium channels
gptkbp:meltingPoint
198-199°C
gptkbp:metabolism
liver
gptkbp:pregnancyCategory
gptkb:C_(Australia)
gptkbp:proteinBinding
>98%
gptkbp:PubChem_CID
gptkb:CHEMBL1423
DB00555
59377
65978
gptkbp:routeOfAdministration
oral
gptkbp:sideEffect
edema
headache
palpitations
flushing
gptkbp:synonym
gptkb:Zanidip
gptkb:Lercadip
gptkbp:UNII
8JZ2786R6F
gptkbp:usedFor
hypertension
gptkbp:bfsParent
gptkb:Recordati
gptkb:Servier_Pharmaceuticals
gptkbp:bfsLayer
7